@font-face {
  font-family: Roboto;
  src: url('fonts/Roboto-Regular.ttf');
  font-weight: normal;
  font-style: normal;
}

:root {
  --bg-panel-color: #F4F7FE;
  /* --bg-panel-color: #F3F5F8; */
  --app-blue: #005C75;
  --bs-body-font-size: .9rem;
  --benign-color: #226e34;
  --likely-benign-color: #0e8029;
  --uncertain-significance-color: rgb(162, 162, 162);
  --likely-pathogenic-color: #d25858;
  --pathogenic-color: #9f3232;
  --star-yellow: #FDB81E;
  --star-gray: #CFCFCF;
  --orange: #e67e22;
}

.titlebar {
    height: 62px;
    width: 100%;
    color: white;
    display: flex;
    background: #254053;
    justify-content: center;
    align-items: center;
    -webkit-app-region: drag;
}

.row {
    margin-top: 3px;
}

canvas:focus {
    outline: none;
}

.cursor-pointer {
    cursor: pointer;
}

p {
    color: rgba(73, 80, 87, .85);   
}

body {
    margin: 0px;
    font-family: Roboto;
}

nav {
    display: block;
    unicode-bidi: isolate;
}

ul {
    display: block;
    list-style-type: disc;
    margin-block-start: 1em;
    margin-block-end: 1em;
    margin-inline-start: 0px;
    margin-inline-end: 0px;
    padding-inline-start: 40px;
    unicode-bidi: isolate;
}

.sidebar {
    min-width: 270px;
    max-width: 270px;
    /*transition: margin-left .35s ease-in-out, left .35s ease-in-out, margin-right .35s ease-in-out, right .35s ease-in-out;
    direction: ltr;*/
    background: #293042;
}

*,*:before,*:after {
    box-sizing: border-box
}


.sidebar-link, a.sidebar-link {
    display: block;
    padding: .625rem 1.625rem;
    font-weight: 400;
    transition: color 75ms ease-in-out;
    position: relative;
    text-decoration: none;
    cursor: pointer;
    color: #e2e8ee80;
}

.sidebar-link-active {
    color: white !important;
}

li {
    text-align: -webkit-match-parent;
}

.sidebar-nav {
    padding-left: 0;
    list-style: none;
}


.brand-name {
    font-weight: 600
}

.nav-search {
    width: 500px !important;
}

.nav-element {
    color: #495057;
}

.navbar {
    padding: 7px 10px 7px 10px;
}
.navbar .form-control {
    max-width: 500px !important;  
}

.sidebar-header {
    font-size: 16px;
}

.sidebar-dropdown {
    margin: 0px;

}

ul {
    list-style-type: none;
  }


.sidebar-dropdown .sidebar-link {
    padding: .25rem 1.5rem .25rem 3.7rem;
    
}

.sidebar-link, a.sidebar-link {
    padding: .225rem 1.625rem;
}

.sidebar-dropdown {
    transition: height ease .4s;
}


.modal-body {
    background-color: var(--bg-panel-color);
}

.modal-footer-extended {
    padding: 10px;
    background-color: white;
    border-top: 1px solid #e7e7eb;
    border-bottom-right-radius: var(--bs-modal-inner-border-radius);
    border-bottom-left-radius: var(--bs-modal-inner-border-radius);
}

.trumbowyg-box,
.trumbowyg-editor {
    min-height: unset!important;
}

.trumbowyg-editor, 
.trumbowyg-textarea {
    min-height: 200px!important;
    resize: vertical!important;	
}


.btn-primary {
    background-color: #3F80EA !important;
    border-color: #3F80EA !important;
}

.btn-primary:hover {
    background-color: #366dc7 !important;
    border-color: #366dc7 !important;
}

.btn-download {
    background-color: rgb(14, 132, 32);
    border-color: rgb(14, 132, 32);
    width: 100%;
    padding-top: 9px !important;
    padding-bottom: 9px !important;
    color: #fff;
    transition-duration: .1s;
    transition-property: background-color, border-color;
    transition-timing-function: cubic-bezier(0.55, 0.055, 0.675, 0.19);
    border-radius: .125rem;
    border-style: solid;
    border-width: 1px;
    cursor: pointer;
    display: inline-block;
    font-size: 1rem;
    font-weight: 300;
    justify-content: center;
    line-height: 1.5rem;
    margin: 0 0 1.2rem 0;
    text-align: center;
    text-decoration: none !important;
}

.btn-download:hover {
    background-color: #0f661C;
    border-color: #0f661C;
    color: white;
    text-decoration: none;
}


.dropdown-divider {
    border-top: 1px solid #eeeeee !important;  
}

.button-hg19 {
    background: #06a2a8 !important;
    color: white !important;
    border: 1px solid #dce0e0 !important;
}

.button-hg19:hover {
    background: #ffffff !important;
    color: black !important;
}

.button-hg38 {
    background: #006c70 !important;
    color: white !important;
    border: 1px solid #dce0e0 !important;
}

.button-hg38:hover {
    background: #ffffff !important;
    color: black !important;
}

.button-hs1 {
    background: #ff8d90 !important;
    color: white !important;
    border: 1px solid #dce0e0 !important;
}

.button-hs1:hover {
    background: #ffffff !important;
    color: black !important;
}

.button-link {
    padding: 6px 12px !important;
}


.navbar {
    z-index: 200;
}

.left-panel {
    left: 270px; 
    top: 62px; 
    background-color: var(--bg-panel-color);
    border-right: 1px solid #e7e7eb;
    height: calc(100vh - 62px); 
    position:absolute; 
    z-index: 101;
    display: none;
    box-shadow: 0 0 1rem #2930421a; 
    transition: margin-left .65s ease-in-out, left .35s ease-in-out, margin-right .35s ease-in-out, right .35s ease-in-out;
}

.right-panel {
    right: 0px;
    top: 62px;
    background-color: var(--bg-panel-color);
    border-left: 1px solid #e7e7eb;
    height: calc(100vh - 62px);
    position:absolute;
    z-index: 101;
    display: none;
    box-shadow: 0 0 1rem #2930421a;
    transition: margin-left .65s ease-in-out, left .35s ease-in-out, margin-right .35s ease-in-out, right .35s ease-in-out;
}

.panel-content {
    padding-top: 40px !important;
    text-align: left;
    padding: 20px;
    overflow: auto; 
    height: calc(100vh - 62px - 55px);
}

.panel-footer {
   padding: 10px;
   background-color: white;
   border-top: 1px solid #e7e7eb;
   height: 55px;
   position: absolute;
   bottom: 0px;
   z-index: 102;
   width: 100%;
}

.text-label {
    margin-top: 6px !important;
    margin-bottom: 6px !important;
}

.text-value {
    color: #293042;
}


.variant-source-title {
    font-size: 1.05em;
    font-weight: 500;
    color: #3a4257;
}


.transcript-row {
	min-height: 20px;
}

.transcript-row > td {
	padding-top: 6px;
	padding-bottom: 6px;
}

.transcript-row-selected {
	border-left: 3px solid var(--app-blue) !important;
	background-color: #eeeeee;
}





.h1, .h2, .h3, .h4, .h5, .h6, h1, h2, h3, h4, h5, h6 {
    color: #495057;
    font-weight: 500;
    line-height: 1.2;
    margin-bottom: .8rem;
    margin-top: 0.3rem;
}


.h3, h3 {
    font-size: 1.3125rem;
    color: #2c3857;
}

.h4, h4 {
    font-size: 1.0.9375rem;
}
.h5, h5 {
    font-size: 1.0.9375rem;
}

.card-header {
	padding: 10px 16px 0px 16px;
}

.card-body {
	padding: 10px 16px 10px 16px;
}

.card-add-track-body {
    border-top: 1px solid lightgray;
}

.card-add-track {
    height: 355px;
    cursor: pointer;
}

.card-add-track:hover {
   box-shadow: 0 .225rem .5rem rgba(0,0,0,.1) !important;
}


/* width */
::-webkit-scrollbar {
  width: 7px;
  height: 9px;
}

 
/* Handle */
::-webkit-scrollbar-thumb {
  background: #d8d8d8; 
  /* -webkit-box-shadow: inset 0 0 6px rgba(0,0,0,0.3); */
  border-radius: 3px;
}

/* Handle on hover */
::-webkit-scrollbar-thumb:hover {
  background: #d1d1d1; 
}


.trumbowyg-editor-box {
    background-color: white !important;
}


/********************
 * BUTTONS
 ********************/
.btn {
  -webkit-border-radius: 2px;
  -moz-border-radius: 2px;
  border-radius: 4px;
  -moz-box-shadow: 0px 1px 2px 0 rgba(0, 0, 0, 0.2);
  -webkit-box-shadow: 0px 1px 2px 0 rgba(0, 0, 0, 0.2);
  box-shadow: 0px 1px 2px 0 rgba(0, 0, 0, 0.2);
  padding: 6px 22px; 
  border: 1px solid transparent !important;

}
 

.btn-group-lg > .btn,
.btn-lg {
  padding: 10px 28px; }

.btn-group-sm > .btn,
.btn-sm {
  padding: 5px 18px; }

.btn-group-xs > .btn,
.btn-xs {
  padding: 5px 14px; }

.btn-primary {
  background-color: #00AAFF;
  border-color: #00a0f0; 
}

.btn-primary:hover, .btn-primary:focus {
    background-color: #00a0f0;
    border-color: #00a0f0; 
}

.btn-warning {
  background-color: #e4cb10;
  border-color: #d6be0f; 
}

.btn-warning:hover, .btn-warning:focus {
    background-color: #d6be0f;
    border-color: #d6be0f; 
}


.btn-default, .btn-cancel{
    color: #333;
    background-color: #fff;
    border-color: #ccc !important;
}

.btn-default:hover, .btn-default:focus, .btn-cancel:hover, .btn-cancel:focus {
  background-color: #f7f7f7; 
}

.btn-success {
  background-color: #41B314;
  border-color: #3ca512; }

.btn-success:hover, .btn-success:focus {
    background-color: #3ca512;
    border-color: #3ca512; 
}

.btn.disabled,
.btn[disabled],
fieldset[disabled] .btn {
  opacity: 0.4;
  filter: alpha(opacity=40); }






.main-wrapper {
	display: flex; 
	width: 100%;
}



.contextMenu {
    position: absolute;
    display: none
}

.divider {
    margin-top: 6px;
    margin-bottom: 6px;
    height: 1px;
    background-color: #dee2e6
}

.menu-icon {
    margin-right: 15px
}

.tooltip-menu {
    margin-left: 10px !important;
    padding-left: 20px;
    padding-right: 20px;
    font-family: Circular, -apple-system, BlinkMacSystemFont, Roboto, Helvetica Neue, sans-serif;
    font-size: 1em !important;
    line-height: 1.73;
    color: black;
    font-weight: 400;
    -webkit-font-smoothing: antialiased;
    opacity: 0.92;
    filter: alpha(opacity=85)
}

.hr-tooltip {
    padding-top: 0px;
    padding-bottom: 0px;
    margin-top: 4px;
    margin-bottom: 4px
}

.tooltip-title {
    font-size: 1.2em !important;
    line-height: 1.73;
    font-weight: 500
}




/***********************************************
	TOOLTIP Splicing dots
***********************************************/

.splicing-acceptor-dot {
    height: 15px;
    width: 15px;
    background-color: #3cb567;
    border-radius: 50%;
    display: inline-block;
    margin-right: 8px;
  }
  
  .splicing-donor-dot {
    height: 15px;
    width: 15px;
    background-color: #2f5799;
    border-radius: 50%;
    display: inline-block;
    margin-right: 8px;
  }
  
  .splicing-branchpoint-dot {
    height: 15px;
    width: 15px;
    background-color: #B8959B;
    border-radius: 50%;
    display: inline-block;
    margin-right: 8px;
  }
  











.autocomplete {
    position: relative;
    display: inline-block;
    width: 100%;
}

.autocomplete-items {
    position: absolute;
    border: 1px solid #e9e9e9;
    border-bottom: none;
    border-top: none;
    z-index: 16000;
    top: 100%;
    left: 0;
    right: 0;
    border-top: 1px solid #d4d4d4;
}

.autocomplete-item {
    padding: 6px 10px 6px 10px;
    cursor: pointer;
    background-color: #fff;
    border-bottom: 1px solid #e9e9e9;
}

.autocomplete-item:hover {
    background-color: #f2f2f2;
    cursor: pointer;
}











/********************
 * SWITCH
 ********************/
.form-check {
    display: block;
    min-height: 1.340625rem;
    padding-left: 1.5em;
    margin-bottom: .125rem;
}

.form-check .form-check-input {
    float: left;
    margin-left: -1.5em
}

.form-check-reverse {
    padding-right: 1.5em;
    padding-left: 0;
    text-align: right
}

.form-check-reverse .form-check-input {
    float: right;
    margin-right: -1.5em;
    margin-left: 0
}

.form-check-input {
    --bs-form-check-bg: var(--bs-secondary-bg);
    flex-shrink: 0;
    width: 38px;
    height: 20px;
    margin-top: .3125em;
    vertical-align: top;
    -webkit-appearance: none;
    -moz-appearance: none;
    appearance: none;
    background-color: var(--bs-form-check-bg);
    background-image: var(--bs-form-check-bg-image);
    background-repeat: no-repeat;
    background-position: center;
    background-size: contain;
    border: var(--bs-border-width) solid var(--bs-border-color);
    -webkit-print-color-adjust: exact;
    print-color-adjust: exact;
}

.form-check-input[type=checkbox] {
    border-radius: .25em
}

.form-check-input[type=radio] {
    border-radius: 50%
}

.form-check-input:active {
    filter: brightness(90%)
}

.form-check-input:focus {
    border-color: #9fc0f5;
    outline: 0;
    box-shadow: 0 0 0 .25rem #3f80ea40
}

.form-check-input:checked {
    background-color: #3f80ea;
    border-color: #3f80ea
}

.form-check-input:checked[type=checkbox] {
    --bs-form-check-bg-image: url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 20 20'%3e%3cpath fill='none' stroke='%23fff' stroke-linecap='round' stroke-linejoin='round' stroke-width='3' d='m6 10 3 3 6-6'/%3e%3c/svg%3e")
}

.form-check-input:checked[type=radio] {
    --bs-form-check-bg-image: url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='-4 -4 8 8'%3e%3ccircle r='2' fill='%23fff'/%3e%3c/svg%3e")
}

.form-check-input[type=checkbox]:indeterminate {
    background-color: #3f80ea;
    border-color: #3f80ea;
    --bs-form-check-bg-image: url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 20 20'%3e%3cpath fill='none' stroke='%23fff' stroke-linecap='round' stroke-linejoin='round' stroke-width='3' d='M6 10h8'/%3e%3c/svg%3e")
}

.form-check-input:disabled {
    pointer-events: none;
    filter: none;
    opacity: .5
}

.form-check-input[disabled]~.form-check-label,.form-check-input:disabled~.form-check-label {
    cursor: default;
    opacity: .5
}

.form-switch {
    padding-left: 2.5em
}

.form-switch .form-check-input {
    --bs-form-switch-bg: url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='-4 -4 8 8'%3e%3ccircle r='3' fill='rgba%280, 0, 0, 0.25%29'/%3e%3c/svg%3e");
    width: 38px;
    margin-left: -2.5em;
    background-image: var(--bs-form-switch-bg);
    background-position: left center;
    border-radius: 2em;
    transition: background-position .15s ease-in-out
}

@media (prefers-reduced-motion: reduce) {
    .form-switch .form-check-input {
        transition: none
    }
}

.form-switch .form-check-input:focus {
    --bs-form-switch-bg: url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='-4 -4 8 8'%3e%3ccircle r='3' fill='%239fc0f5'/%3e%3c/svg%3e")
}

.form-switch .form-check-input:checked {
    background-position: right center;
    --bs-form-switch-bg: url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='-4 -4 8 8'%3e%3ccircle r='3' fill='%23fff'/%3e%3c/svg%3e")
}

.form-switch.form-check-reverse {
    padding-right: 2.5em;
    padding-left: 0
}

.form-switch.form-check-reverse .form-check-input {
    margin-right: -2.5em;
    margin-left: 0
}

.form-check-inline {
    display: inline-block;
    margin-right: 1rem
}










/********************************************
	LOADER
*********************************************/

.loader {
	height: 100%;
	display: flex;
	align-items: center;
	justify-content: center;
}


.loader-item {
	position: relative;
	display: flex;
	justify-content: center;
	align-content: center;
	width: 120px;
	height: 30px;
}

.dot {
	position: relative;
	flex: 1;
	display: flex;
	justify-content: center;
	align-content: center;
	margin: 0 5px;
	height: 30px;
	width: 2px;
}

.dot:first-of-type 
{ margin-left: 0 }

.dot:last-of-type 
{ margin-right: 0 }

.dot::before,
.dot::after {
	content: "";
	position: absolute;
	bottom: -5px;
	display: block;
	width: 6px;
	height: 6px;
	background: #2C76B8;
	border-radius: 6px;
	box-shadow: 1px 1px 4px rgba(0,0,0,.15);
	animation: helix 1.5s ease-in-out infinite;
}

.dot::after {
	bottom: 100%;
	animation: helix-reversed 1.5s ease-in-out infinite;
}

.dot i {
	position: absolute;
	z-index: 25;
	align-self: center;
	width: 2px;
	height: 20px;
	background: #2C76B888;
	animation: helix-bar 1.5s ease-in-out infinite;
}

.dot2::before, .dot2::after, .dot2 i
{ animation-delay: 0.05s }

.dot3::before, .dot3::after, .dot3 i
{ animation-delay: 0.10s }

.dot4::before, .dot4::after, .dot4 i
{ animation-delay: 0.15s }

.dot5::before, .dot5::after, .dot5 i
{ animation-delay: 0.20s }

.dot6::before, .dot6::after, .dot6 i
{ animation-delay: 0.25s }

.dot7::before, .dot7::after, .dot7 i
{ animation-delay: 0.30s }

.dot8::before, .dot8::after, .dot8 i
{ animation-delay: 0.35s }

.dot9::before, .dot9::after, .dot9 i
{ animation-delay: 0.40s }

@keyframes helix {
	  0% { width: 5px; height: 5px; bottom: -5px; z-index: 10 }
	 25% { width: 2px; height: 2px }
	 50% { width: 5px; height: 5px; bottom: 100%; z-index: 20 }
	 75% { width: 8px; height: 8px }
	100% { width: 5px; height: 5px; bottom: -5px }
}

@keyframes helix-reversed {
	  0% { width: 5px; height: 5px; bottom: 100%; z-index: 20 }
	 25% { width: 8px; height: 8px }
	 50% { width: 5px; height: 5px; bottom: -5px; z-index: 10 }
	 75% { width: 2px; height: 2px }
	100% { width: 5px; height: 5px; bottom: 100% }
}

@keyframes helix-bar {
	  0% { height: 15px }
	 25% { height:  8px }
	 50% { height: 15px }
	 75% { height:  8px }
	100% { height: 15px }
}






.navigation-chevron {
    display: inline-block;
    padding-bottom: 10px;
    padding-left: 5px;
    padding-right: 5px;
    color: #2f5799;
    cursor: pointer;
}

.navigation-chevron:hover {
    color: #4b7bc9;
}

.navigation-card {
    width: 160px;
    position: absolute;
    margin-left: auto;
    margin-right: auto;
    left: 0;
    right: 0;
    margin-bottom: 10px;
    z-index: 2;
    border-radius: 5px;
    border: 1px solid rgb(228, 228, 228);
    box-shadow: rgba(0, 0, 0, 0.2) 0px 0px 5px;
    opacity: 1;
    filter: alpha(opacity = 100);
    background-color: white;
    height: 28px;
}

.navigation-vertical-divider {
    border-left: 1px solid rgb(228, 228, 228);
    position: absolute;
    left: 50%;
    margin-left: -3px;
    top: 0;
    height: 28px;
}



.info-help {
    color: rgb(42, 115, 203);    
    margin-right: 3px;
    margin-left: 3px;
}

.info-help:hover {
    cursor: pointer;
    color: rgb(37, 98, 172);  
}


.text-low {
    color: var(--likely-benign-color);
}

.text-modifier {
    color: var(--uncertain-significance-color);
}

.text-moderate {
    color: var(--orange);
}

.text-high {
    color: var(--pathogenic-color);
}

.class-P {
    color: var(--pathogenic-color);
}
.class-LP {
    color: var(--likely-pathogenic-color);
}

.class-US {
    color: var(--uncertain-significance-color);
}

.class-LB {
    color: var(--likely-benign-color);
}

.class-B {
    color: var(--benign-color);
}


.badge {
    padding: 5px 7px 3px 7px !important;
}

.badge-classification {
    padding: 5px 14px 5px 14px !important;
    border-radius: 12px !important;
    font-weight: 400 !important;
    font-size: 12px;
    margin-bottom: 2px;
    color: white;
    text-wrap: nowrap;
}

.badge-1 {
    background-color: var(--benign-color);
}

.badge-2, .badge-LOW, .badge-FAIBLE {
    background-color: var(--likely-benign-color);
}

.badge-3, .badge-MODIFIER {
    background-color: var(--uncertain-significance-color);
}


.badge-4 {
    background-color: var(--likely-pathogenic-color);
}

.badge-5, .badge-HIGH, .badge-ÉLEVÉ {
    background-color: var(--pathogenic-color);
}

.badge-exon {
    background-color: #f39c12;
}

.badge-intron {
    background-color: var(--uncertain-significance-color);
}

.badge-missense {
    background-color: var(--orange);
}

.badge-synonymous {
    background-color: var(--app-blue);
}

.badge-delins {
    background-color: #d4660c;
}

.badge-start_loss {
    background-color: var(--likely-pathogenic-color);
}

.badge-stop_loss {
    background-color: var(--pathogenic-color);
}

.badge-stop_gained {
    background-color: var(--pathogenic-color);
}

.badge-inframe_deletion, .badge-MODERATE {
    background-color: var(--orange);
}

.badge-inframe_insertion {
    background-color: var(--orange);
}

.badge-splicing_acceptor {
    background-color: var(--likely-pathogenic-color);
}

.badge-splicing_donor {
    background-color: var(--likely-pathogenic-color);
}

.badge-none {
    background-color: var(--uncertain-significance-color);
}

.badge-frameshift {
    background-color: #f35912;
}


.star-yellow {
    color: var(--star-yellow) !important;
}

.star-gray {
    color: var(--star-gray) !important;
}


.card-border-1, .card-border-C0, .card-border-TOLERATED, .card-border-Benign, .card-border-LOW, .card-border-FAIBLE {
    border-left: 4px solid var(--benign-color);
}

.card-border-2 {
    border-left: 4px solid var(--likely-benign-color);
}

.card-border-3 {
    border-left: 4px solid var(--uncertain-significance-color);
}

.card-border-4, .card-border-C15, .card-border-C25, .card-border-C35, .card-border-C45 {
    border-left: 4px solid var(--likely-pathogenic-color);
}

.card-border-5, .card-border-C55, .card-border-C65, .card-border-DELETERIOUS, .card-border-Pathogenic, .card-border-HIGH, .card-border-ÉLEVÉ {
    border-left: 4px solid var(--pathogenic-color);
}

.card-border-blue {
    border-left: 4px solid #2F5799;
}

.variant-link {
    font-size: 18px;
    color:#2c3857;
    font-weight: 600;
    cursor: pointer;
}

.variant-link:hover {
    cursor: pointer;
    color:#1d263a;
}

.card-acmg {

}

.card-acmg:hover {
	cursor: pointer;
	box-shadow: rgba(0, 0, 0, 0.1) 0px 10px 15px -3px, rgba(0, 0, 0, 0.05) 0px 4px 6px -2px;
}

.card-acmg-default {
    border-left: 7px solid #cacaca;
}

.card-acmg-BA {
    border-left: 7px solid #27ae60;
}

.card-acmg-BS {
    border-left: 7px solid #27ae60aa;
}

.card-acmg-BP {
    border-left: 7px solid #27ae6066;
}

.card-acmg-PV {
    border-left: 7px solid #c0392b;
}

.card-acmg-PS {
    border-left: 7px solid #e74c3c;
}

.card-acmg-PM {
    border-left: 7px solid #e67e22;
}

.card-acmg-PP {
    border-left: 7px solid #f39c12;
}


/*  CNV  */

.card-acmg-1A, .card-acmg-3A {
    border-left: 7px solid #cacaca;
}

.card-acmg-1B, .card-acmg-2F {
    border-left: 7px solid #27ae60aa;
}

.card-acmg-3B {
    border-left: 7px solid #e67e22;
}


.card-acmg-2A, .card-acmg-2C, .card-acmg-3C {
    border-left: 7px solid #c0392b;
}



.inline-loader {
    height: 5px;
    width: 100%;
    --c: no-repeat linear-gradient(#6100ee 0 0);
    background: var(--c), var(--c), #d7b8fc;
    background-size: 60% 100%;
    animation: l16 3s infinite;
}
@keyframes l16 {
    0% {background-position: -150% 0, -150% 0}
    100% {background-position: 250% 0, 250% 0}
}


/*****************************************************************************/
.slider-range {
    -webkit-appearance: none;
    width: 270px;
    height: 6px;
    background: #d3d3d3;
    outline: none;
    opacity: 0.7;
    -webkit-transition: .2s;
    transition: opacity .2s;
    border-radius: 3px;
}

.slider-range::before {
    visibility: hidden;
}

.slider-range:hover {
    opacity: 1;
}

.slider-range::-webkit-slider-thumb {
    -webkit-appearance: none;
    appearance: none;
    width: 15px;
    height: 15px;
    background: var(--app-blue);
    cursor: pointer;
    border-radius: 50%;
}

.slider-range::-moz-range-thumb {
    width: 25px;
    height: 25px;
    background:var(--app-blue);
    cursor: pointer;
}









/* Pour l'upload des fichiers*/
.drop-container-modal {
    position: relative;
    display: flex;
    gap: 10px;
    flex-direction: column;
    justify-content: center;
    align-items: center;
    height: 200px;
    padding: 20px;
    border-radius: 10px;
    border: 2px dashed #555;
    color: #444;
    cursor: pointer;
    background: #fcfcfc;
    transition: background .2s ease-in-out, border .2s ease-in-out;
  }
  
  .drop-container-modal:hover {
    background: #eee;
    border-color: #111;
  }
  
  .drop-container-modal:hover .drop-title {
    color: #222;
  }
  
  .drop-title-modal {
    color: #444;
    font-size: 20px;
    font-weight: bold;
    text-align: center;
    transition: color .2s ease-in-out;
  }

  .drop-container-modal.drag-active {
    background: #eee;
    border-color: #111;
  }
  
  .drop-container-modal.drag-active .drop-title {
    color: #222;
  }






/* Pour l'upload des fichiers*/
.drop-container {
    position: relative;
    display: flex;
    gap: 10px;
    flex-direction: column;
    justify-content: center;
    align-items: left;
    height: 50px;
    padding: 20px;
    border-radius: 10px;
    margin: 20px;
    border: 1px dashed #e2e8ee80;
    color: #444;
    transition: background .2s ease-in-out, border .2s ease-in-out;
}

.drop-container:hover {
    background: #eee;
    border-color: #111;
    cursor: pointer;
}

.drop-container:hover .drop-title {
    color: #222;
    cursor: pointer;
}

.drop-title {
    color: #e2e8ee80;
    font-size: 16px;
    text-align: center;
    transition: color .2s ease-in-out;
}

.drop-container.drag-active {
    background: #eee;
    border-color: #111;
}

.drop-container.drag-active .drop-title {
    color: #222;
}

.drop-title:hover {
    cursor: pointer;
}


/*    PDB  */

.msp-plugin .msp-layout-standard {
    border: none !important
}














.diagram-note {
    background-color: rgba(66, 180, 21, 0.7);
    color: White;
    border-radius: 5px;
    font-family: Arial;
    font-size: 12px;
    padding: 5px;
    min-height: 16px;
    width: 50px;
    text-align: center;
}

.needs-discussion:not(.djs-connection) .djs-visual > :nth-child(1) {
    stroke: rgba(66, 180, 21, 0.7) !important; /* color elements as red */
}









/*
html, body {
	display: flex;
	justify-content: center;
	align-items: center;
	margin: 0;
	padding: 0;
	width: 100%;
	height: 100%;
	background: linear-gradient(20deg, #0c57a1, #3f88c5 45%) fixed;
}
*/